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AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS)
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  • Updated HHS Adult and Adolescent Antiretroviral Treatment Guidelines Released
    The HHS Panel on Antiretroviral Guidelines for Adults and Adolescents announces the release of the updated Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents.

    Key updates to the guidelines include additions and changes to the following guideline sections:

    What to Start:
    • Significant changes to the list of Recommended, Alternative, and Other regimens for treatment-naive patients prompted by recent findings from clinical trials and cohort studies, as well as experience in clinical practice.
    • Addition of a new table to assist clinicians in selecting an initial ARV regimen based on specific clinical scenarios and ARV-related considerations.
    Management of the Treatment-Experienced Patient:
    • Expanded information on the management of patients failing first and second ART regimens, and new information about isolated CNS virologic failure and new onset neurologic symptoms.
    • A new section to highlight information on poor CD4 cell recovery and persistent inflammation and the increased risk of morbidity.
    Drug Interactions:
    • A new table outlining the mechanisms of interaction of ARV drugs.
    • Updates to all drug-drug interaction tables, particularly to those related to ritonavir- or cobicistat-boosted ARV drugs.

    In addition, the Acute/Early HIV Infection, HIV-2 Infection, and HIV/Hepatitis C Virus (HCV) Coinfection sections have been updated to reflect the most recent information relevant to each section.

    For a complete preview of key updates to the guidelines, please see What's New in the Guidelines. Additions and revisions are also highlighted in yellow throughout the text and tables of the PDF version of the guidelines.

    To view or download the guidelines, go to the Adult and Adolescent ARV Guidelines section of AIDSinfo. Separate PDF files of only the guideline tables or the boxed recommendations can also be downloaded from the page.

    Forward Comments on the Revised Guidelines to AIDSinfo

    Feedback on the revised Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents is welcome. Please e-mail your comments with the subject line "Comments on the Adult and Adolescent ARV Guidelines" to ContactUs@aidsinfo.nih.gov by April 24, 2015.
  • Recent HIV/AIDS News from FDA, NIAID, and NIH
  • Revised Hepatitis B Virus (HBV) Section of the Adult and Adolescent Opportunistic Infection (OI) Guidelines Released
     
    There is new information on techniques to evaluate the stage of liver fibrosis. New data on HBV immunization regimens is included in recommendations regarding the choice of the optimal immunization regimen. There are also new recommendations regarding the duration of anti-HBV therapy following initiation of ART.
     
    Please send your comments with the subject line "Comments on Adult and Adolescent OI Guidelines" to ContactUs@aidsinfo.nih.gov by April 30, 2015.
  • "Drugs That Fight HIV-1" Brochure Recently Updated
    The "Drugs That Fight HIV-1" brochure has been updated to include antiretroviral (ARV) drugs recently approved by FDA. The NIH publication features images of FDA-approved ARVs, grouped by drug class and identified by both generic and brand names. The brochure, available in both English and Spanish, offers health care professionals a visual aid to use when discussing HIV treatment with patients.

    The brochure can be found in the HIV/AIDS Images section of Health Topics on our website.
     
    For more information on FDA-approved and investigational HIV/AIDS-related medications, please visit our Drug Database or download the AIDSinfo Drug Database app. The free app provides on-the-go access to the same information found in our Drug Database. The app is available for Apple and Android devices and allows users to bookmark frequently referenced drugs, add notes to drugs, or use an alarm feature to set pill reminders for any drug.
  • National Library of Medicine Announces Solicitation of Quotations for the 2015 HIV/AIDS Community Information Outreach Projects
    The National Library of Medicine (NLM) is pleased to announce the solicitation of quotations from organizations and libraries to design and conduct projects for improving HIV/AIDS information access for patients and the affected community as well as their caregivers and the general public. Patients and the affected community need access to the most up-to-date and accurate health information to effectively manage and make informed decisions about their health. Health care providers and health educators also need access to the most current information to provide the highest quality of care. NLM is committed to assisting organizations in accessing the spectrum of information resources and services that are currently available. The NLM is particularly interested in proposals with creative and different approaches to disseminate information to populations that have a disproportionate prevalence of HIV/AIDS infections in the United States. These populations include but are not limited to men who have sex with men (MSM), African Americans, and Hispanic/Latinos.    

    Emphasis is on increasing the awareness and utilization of NLM online health and medical resources in the HIV/AIDS Community through the use of innovative and evidence-based projects.

    Projects must involve two or more of the following information access categories:
    • Information retrieval; 
    • Skills development; 
    • Resource development and dissemination; and/or 
    • Equipment acquisition.
    Significance is placed upon the following types of organizations or arrangements for developing these programs:
    • Community-based organizations (CBOs) or patient advocacy groups currently providing HIV/AIDS-related services to the affected community; 
    • Public libraries serving communities in the provision of HIV/AIDS-related information and resources; 
    • Health departments or other local, municipal, or state agencies working to improve public health; 
    • Faith-based organizations currently providing HIV/AIDS-related services; and/or 
    • Multi-type consortia of the above-listed organizations that may be in existence or formed specifically for this project.
    Awards are offered for up to $50,000.

    Quotations are due to NLM on July 20, 2015.

    The solicitation for the 2015 HIV/AIDS Community Information Outreach Projects is posted on the Federal Business Opportunities website: https://www.fbo.gov/spg/HHS/NIH/OAM/NIHLM2015468/listing.html

    Primary Point of Contact: 
    Greg Benedict, Contract Specialist
    Office of Acquisitions (OA)
    National Library of Medicine (NLM)
    6707 Democracy Blvd., Suite 105
    Bethesda, Maryland 20892-5488
    301-496-6546
    Fax: 301-402-0642
    E-mail: Gregory.benedict@nih.gov
     
    Secondary Point of Contact: 
    Shari Shor, Contracting Officer
    Office of Acquisitions (OA)
    National Library of Medicine (NLM)
    6707 Democracy Blvd. Suite 105
    Bethesda, MD 20892-5488
    Office Phone: 301-496-6546
    Fax: 301-402-0642
    E-mail: shorse@mail.nlm.nih.gov

    Please Note: Refer to the Federal Business Opportunities website for notices, updates, and modifications to the HIV/AIDS Community Information Outreach Project 2015 RFQ.
  • May 18 is HIV Vaccine Awareness Day
    Join AIDSinfo in observing HIV Vaccine Awareness Day on May 18. The annual observance is dedicated to the many scientists, health professionals, community members, and volunteers who are collaborating to develop both preventive and therapeutic HIV vaccines.

    Visit our HIV Vaccine Awareness Day webpage to learn more about the annual observance and about advances in HIV vaccine research.